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Frequently asked questions about steroids

Frequently asked questions about steroids
  • How much weight can someone expect to gain during the first cycle of steroids? Provided dosing is sufficient, a steroid user can expect to make the most significant progress during their first cycle. Although this will vary from person to person, it is not uncommon for someone to gain 20 pounds of weight or more during a 6-8 week period of AAS use. Some of this may be water retention, although a solid gain of more than 10-15 pounds of muscle mass is possible.
  • Are the gains from steroid use temporary? Yes, and no. Steroids can help you do two basic things with regard to muscle growth. First, they can allow you to more rapidly reach your genetic limits for muscle growth. Provided you continue to train actively, eat properly, and use an effective PCT program, you should be able to maintain at your genetic limit indefinitely. So in this regard, the early gains do not have to be temporary. Later, steroids can allow you to push well beyond your genetic limits. It is important to emphasize this, as extreme physical development cannot be maintained long-term without the repeat administration of anabolic substances. The body will always revert back towards its normal metabolic limits once AAS are removed. In this context, some of the gains will not be permanent. Steroids do permanently alter the physiology of your muscles by adding more cellular nuclei. With higher nuclei content, each muscle cell can manage its volume more efficiently, which allows more rapid expansion. Even after a long period of complete abstinence from training and AAS, the nuclei remain. This may provide a “muscle memory” effect, allowing you to reach your genetic limit (perhaps a slightly extended limit) faster than if you had never used AAS in the past. So in this regard, there are lasting benefits beyond the temporary increase in muscle size itself.
  • Can steroids make me look like a professional bodybuilder? If you have the underlying genetics to allow for this extreme muscle growth, this may be possible with a lot of hard work and dedication. If you are like the vast majority of people, however, steroids will not be able to make you look like a professional bodybuilder. Genetics are a big factor in determining the ultimate limits to your physique, even in an enhanced state. Many people use steroids and look very big and impressive because of it, but very few users are able to make it to the stage of a professional bodybuilding show.
  • How dangerous is an isolated cycle of steroids? Anabolic/androgenic steroids are among the safest drugs available, at least in a short-term sense. Fatal overdose is not reasonably possible, and the negative health changes such as alterations in cholesterol, blood pressure and blood clotting (among other things) are very unlikely to manifest in serious bodily harm or death after an isolated cycle. There are rare deaths from such things as stroke and liver cancer in short-term abusers, but such occurrences are statistically extremely rare in light of the millions of people that use these drugs. If you had to comparatively rate the acute risks of AAS abuse, they would be slightly higher than marijuana, but far less than virtually all other illicit narcotics.
  • How dangerous is long-term steroid use? The long-term use of steroids for non-medical reasons can be a significantly unhealthy practice. It has been difficult, however, to quantify the exact risk. The main issue is the fact that AAS abuse can promote heart disease, the number one killer of men. Heart disease is a slow progressive disease, which may build for decades without symptoms. Steroid abuse may accelerate the silent process of plaque deposition in the arteries, and also induce other changes in the cardiovascular system that can increase susceptibility to stroke or heart attack. If death finally occurs, however, it will be difficult for a medical examiner to pinpoint AAS as the cause; too many variables play a role in the etiology of cardiovascular disease. The vast majority of deaths where AAS have contributed go unreported for this reason. The exact mortality rates of long-term steroid abusers have, likewise, been difficult to calculate. According to one population-based study, steroid abusers had a 4.6 times greater risk of early death from all causes including suicide compared to non-users. It is unknown, however, how applicable this number is to the full steroid-using population. It is especially important to closely monitor cardiovascular disease and other health risk factors if long-term steroid use is a practice you will follow.
  • Can steroids be used to enhance an athletic career safely? The non-medical use of AAS by definition cannot be defined as a safe practice. However, it can be argued that anabolic/androgenic steroids can be used with high relative safety, even over a period of many years. The guidelines of steroid harm reduction are important to minimizing the negative health effects of these drugs. Provided an individual follows these guidelines and is careful with drug selection, dosages, and durations of intake, follows a diet low in saturated fats, cholesterol, sugar, and refined carbohydrates, actively trains with both resistance and cardiovascular exercise, and uses cholesterol support supplements such as fish oils and Lipid Stabil during all cycles, it may be difficult in many cases to argue high tangible health risks. It takes a great deal of involvement and planning to use AAS in this manner, which is always advised.
  • What are the safest steroids for men? Testosterone, whatever the form, tends to be the safest steroid for men. When the dose remains within the moderately supra-therapeutic range (such as 200-400 mg of an injectable testosterone ester per week), alterations in cardiovascular risks factors are noticed, but not extreme. Some of this has to do with the beneficial cardiovascular effects of estrogen in men. Also considered fairly safe are the common injectable steroids boldenone, nandrolone, and methenolone. Isolating your use to these drugs is recommended over using the full spectrum of oral and injectable steroids.
  • What steroids will not cause hair loss? For those with a genetic predisposition to hair loss, all anabolic/androgenic steroids are capable of accelerating the process. Slowing the onset of this during AAS use requires a focus on reducing relative androgenicity in the scalp. This can be accomplished with the use of predominantly anabolic drugs such as nandrolone, oxandrolone, or methenolone. Alternately, moderate doses of testosterone can be used with finasteride, a drug that reduces DHT conversion (and androgenic amplification) in the scalp. Still, those genetically prone to hair loss can have problems with any steroid, and are always advised to limit dosing, drug intake durations, and monitor effects on the hairline closely.
  • What are the safest steroids for women? Women are generally most concerned with the virilizing (masculinizing) effects of anabolic/androgenic steroids. The least virilizing agents are those with the highest relative anabolic to androgenic effect, such as nandrolone, oxandrolone, and methenolone. Care must always be taken, however, as all AAS are based on male sex steroids, and as such can cause masculinizing effects in women.
  • Should I rotate my steroids every few weeks to prevent receptor down regulation? No, this is not necessary. Anabolic/androgenic steroids all work primarily by attaching to and activating the same receptor. As such, you do not gain anything by switching to a new compound that works via stimulating the same receptor. If tolerance were induced by one AAS compound, it would be extended to all compounds. The plateau effect that is noticed 6-8 weeks into most cycles is poorly understood, but likely related to the new metabolic limits placed on muscle cells under the influence of a certain AAS dosages, not insensitivity to AAS. Classic down regulation does not occur with these drugs, and even if it did, rotating steroids would not prevent it.
  • Should I rotate my steroids every few weeks to prevent receptor down regulation? No, this is not necessary. Anabolic/androgenic steroids all work primarily by attaching to and activating the same receptor. As such, you do not gain anything by switching to a new compound that works via stimulating the same receptor. If tolerance were induced by one AAS compound, it would be extended to all compounds. The plateau effect that is noticed 6-8 weeks into most cycles is poorly understood, but likely related to the new metabolic limits placed on muscle cells under the influence of a certain AAS dosages, not insensitivity to AAS. Classic down regulation does not occur with these drugs, and even if it did, rotating steroids would not prevent it.

Similar articles to read:

Principles of Anabolic Steroid Harm Reduction

How Long Do Steroids Stay In Your System?

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Strength workout to boost immunity

Strength workout to boost immunity

Frequent exercise enhances and may even delay the ageing of your immune system, according to a review in Frontiers in Immunology. The belief that your immune system is temporarily suppressed post-workout is shifting.

“Researchers had thought that because there are fewer immune cells in your blood one or two hours after exercise, those cells were dying or being deleted,” says lead author John Campbell, Ph.D. “Actually, those cells are moving to other parts of the body and into other tissues to look for potential pathogens.”

In fact, he says, the harder you go, the more immune cells move into the blood and then off hunting pathogens. Your best bet? Exercise on the regular, and mix up your intensity.

Another exercise benefit is that the lean muscle you build revs not only your metabolism but also your immunity: “If you have a higher muscle mass and you exercise, certain proteins are released from the muscle, and this is thought to have protective effects against cancer and other diseases,” says Campbell.

“You want to train to maintain your functional longevity,” says Jay Wright, the founder and CEO of the Wright Fit and TWF Performance Lab in New York and a Shape Brain Trust member. “Human beings were designed to run, jump, lift, and carry things, so we design routines around compound exercises that reinforce our natural movement patterns.”

Start with this do-it-all functional strength routine from Lauren Bustos, trainer at Performance Lab by The Wright Fit. It’ll build functional strength, get your heart rate up, and challenge you just enough to boost your immune system without totally knocking you off your feet.

For the full article, click here.

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What is Bitcoin and how can I pay by Bitcoin?

How to use Bitcoin to pay

WHAT IS BITCOIN?

Bitcoin is a digital currency that is not controlled by central authorities or banks. Bitcoin is completely decentralized. Users can regard it as cash on the Internet. Bitcoins, unlike dollars and euros, exist only in electronic form, are created by people and organizations managing computers around the world, using software that solves mathematical problems. Any user who has a computer/smartphone and Internet access is able to use it. In addition, bitcoins represent a cryptocurrency – a new category of money that is gaining popularity. There are many useful articles about Bitcoin that you might want to read before you start with Bitcoin. Here you can relevant details about it: bitcoin.org/en/faq

WHY SHOULD I USE BITCOIN?

  • It’s anonymous. You remain anonymous! Any wallet can have as many addresses as possible to receive and send bitcoins. Your personal information is in no way connected with them! Account verification may be required for some exchanges (places where you can buy bitcoins for fiat (USD, EURO, etc.), but it is not obligatory for your personal wallet/wallets. Your bitcoin wallet is linked to your account if you buy bitcoin in Coinbase. But information about the place and purpose of sending bitcoin will not be known. In order to improve the security level, you can use temporary intermediate wallets.
  • It requires significantly less time for payment confirmation. We might need 1-2 days to process and confirm your Western Union and MoneyGram payments and 10-20 minutes for the Bitcoin ones. Faster your payment will be confirmed, faster we will ship your order and faster it will be delivered!
  • Bitcoin is not backed by any single bank or country. It’s decentralized. There is no authority to block a bitcoin transaction. And there are no reasons to do so. You already know it, Western Union and MoneyGram transactions could be blocked sometimes for a reason that might be from a good one to the most stupid one. A blocked transaction will require your time and additional costs to resend us the payment.
  • 365 days a year and 24 hours a day – Bitcoin payments are always available. Just make sure that your Internet connection is up and running. It’s like PayPal, credit/debit cards or any other online payment method you are used to, but with a much higher level of anonymity.

HOW AND WHERE CAN I GET BITCOINS?

A lot of exchanges on the Internet provide you with a possibility to buy bitcoins for £, EURO or your local currency through the convenient payment methods (Visa \ MasterCard, PayPal, etc.). Further, you can see the most well-known exchanges that you can trust.Please note! User verification will be required by that majority of the resources below before buying bitcoins according to KYC/AML regulations (Know Your Customer/Anti Money Laundering). This procedure is formal and is carried out just once (when creating an account).

Please note that we have no affiliations with the following websites. The following list is for informational purpose only. Caution should be taken when dealing with your hard-earned money.

Bitcoin UK looks like a serious company with lots of good reviews on Truspilot. They have educational sections to read and watch about Bitcoin and get a general idea of how it works as well as buying options with your bank account or credit card.

CEX.IO is a simple platform that allows you to use VISA / MasterCard to acquire bitcoins. In order to start using this site, you just need to follow the link cex.io/cardsand click on the “Get started” button.

LocalBitcoins is one of the first and most famous exchanges. Users often compare it to eBay because it is a p2p (person to person) platform. Bidding approaches in this case since sellers and buyers agree on all the trading details themselves before the transaction is made. You can buy bitcoins without any ID on LocalBitcoins, purchase it cash using cash deposit or during a personal meeting using just cash. This site is used in 13924 cities and 248 countries. Escrow and dispute resolution are provided on the website.

Some other platforms with good reputation are:

Coinmama

Wires

Binance Jersey

ChangeHero

HOW CAN I TRANSFER/RECEIVE BITCOINS?

Your bitcoins are collected in your wallet software available for almost all operating systems. However, you should be careful with all the info provided. In case you miss or eliminate your wallet-file and don`t have any backup or recovery info you will lose your money. The full list of official wallets for all platforms can find here: bitcoin.org/en/choose-your-wallet

USING A CREDIT CARD

You can visit Bitcoin UK and use online bank transfer or your credit card to buy Bitcoin and then use it to spend on your purchases including ones in our website. Similar websites offer similar methods for buying bitcoin with your credit card. Please visit them and proceed.

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Muscle Growth

Muscle Growth Pharmabol UK

Muscle growth happens by way of 2 mechanisms:
(1) The enlargement of individual muscle cells and muscle fibers via elevated
protein synthesis caused by anabolic substances. This is the first growth mechanism and
its called hypertrophy. Androgens such as testosterone (endogenous or exogenous) and
all AAS have the greatest effect at this level.
(2) The second is called hyperplasia which involves the formation of new muscle
cells and fibers. Though hyperplasia has not been proven in humans, there is a great deal
of research creating great doubt that it does not. As example…a study involving a group
of college students that were untrained, and a group of competitive bodybuilders that
were. Obviously the bodybuilders had much larger arm measurements, yet when muscle
biopsies were performed on both groups the individual muscle fibers were identical.
Since the bodybuilders had significantly “more” fibers, the researchers theorized that they
must have experienced hyperplasia.
Another study on power lifters told the story much more clearly. Two groups of
highly trained power lifters were divided in two (groups that is). One group had trained
life-long steroid free while the other group had an average of 9 years of steroid use. The
steroid group had cycled Anadrol-50, Winstrol-V, Primobolan, Deca Durabolin,
Masteron, and Proviron off and on in various combinations for that period. The steroid
group showed a significant increase in the “number” of muscle fibers when compared to
the drug free power lifters. In the steroid group, researchers also noted an increase in the
number of muscle cell nuclei and an enhanced proportion of newly formed muscle fibers.
These new fibers with more nuclei were formed from satellite-cells. Satellite cells are
immature muscle cells. That is HYPERPLASIA.
Another finding that is equally amazing is that the satellite-cells were found to
have a higher number of androgen receptors. This means that the new cells/fibers have a
greater capacity to use androgens such as AAS. This study showed that the size of the
muscle cell reflects the number of cell nuclei. This study also showed that there was an
increase in satellite-cell numbers in the steroid group significantly higher when compared
to the drug free group.. So what does this all mean?
Intense training with heavy weights creates a stress on muscle fibers and cells
high enough to cause hyperplasia and cellular growth. Those who utilize AAS as part of
their training protocol accelerate these responses to the training stimuli. The newly
formed muscle cells and fibers have a higher content of androgen receptors so AAS work
better on these new cells. Since AAS cause an increase in muscle cell DNA andtherefore increases protein synthesis with no increase in catabolism, (actually AAS
decrease the normal rate of catabolism) the formation of new cells and fibers is
accelerated. Bigger muscles! An important point to add is that years of training intensely
can pay off for those who do not give up training without AAS. New fibers added to
existing fibers means more fibers that can grow. In theory, this suggests AAS, which are
highly anabolic, (protein synthesis) would be advantageous over those providing higher
androgen qualities for long term gains. This is, in part, why more lean mass has been
retained post-cycle when high anabolic/ low-moderate androgenic steroids were utilized.

  • Satellite-cell production and subsequent fiber inclusion are predominantly stimulated by IGF-1
    and FGF (See IGF-1 and FGF for more info).

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Principles of Anabolic Steroid Harm Reduction

Anabolic Steroid Harm Reduction
  • Think of Testosterone First. Of all the anabolic/androgenic steroids produced, testosterone esters like cypionate, enanthate, and Sustanon tend to have the lowest negative impact on health when taken in muscle building and performance-enhancing doses. Testosterone drugs provide a hormone identical to that already produced in the body, presenting the same spectrum of physical and physiological effects. In addition to being one of the most efficient muscle-builders available, testosterone generally has a positive (not negative) effect on libido, supports a positive mood, and supplements necessary estrogen so that cholesterol levels are less negatively shifted. The exclusive use of testosterone drugs for body or performance enhancement is advised if possible.
  • Use Health Support Supplements. Anabolic/androgenic steroid users can help lower the negative health impact of steroid use with the consumption of natural health support supplements. To begin with, the negative cardiovascular effects of these drugs can be offset (at least to some degree) with cholesterol supplements. Fish oil is recommended as a base, which should be stacked with a number of other clinically studied cholesterol support ingredients including green tea, garlic powder, resveratrol, phytosterols, niacin, and policosinol. The blended product Lipid Stabil (Molecular Nutrition) includes these ingredients and is recommended. Cholesterol support supplements should be taken at all times during anabolic steroid therapy. Next, those taking oral steroids should be reducing liver strain with a liver support supplement. Recommended products include Liver Stabil (Molecular Nutrition), Liv-52 (Himalaya Drug Company), and Essentiale Forte (Aventis). One of these products should be taken at all times during therapy with hepatotoxic agents.
  • Always Cycle Steroids. A steroid cycle usually consists of 6 to 12 weeks of drug use followed by an equal period of time or more abstaining from all anabolic/androgenic steroids. This practice is advised for a number of reasons. For one, as you supplement male steroid hormones your body will reduce the production of its own testosterone. Cycling helps reduce the risk of developing long-term fertility and hormonal issues, which are sometimes caused by the uninterrupted use of steroids for many months or years. Cycling also lets your general markers of health (such as cholesterol levels, hematocrit, and blood pressure) return to their normal state periodically, reducing the impact temporary changes may have over time. Those individuals who use anabolic/androgenic steroids for long periods of time without interruption run a greater risk that these negative changes in health markers will result in long-term health issues.
  • Use Reasonable Dosages. High doses of steroids are not necessary to achieve significant muscle growth, especially if moderate physique or performance enhancement is desired. A dosage limit of 400 mg per week on injectables is advised. In the case of testosterone cypionate, 400 mg per week equates to at least 4 to 5 times the level of hormone naturally produced in a healthy male body. This level of use will produce dramatic muscle gain if combined with proper training and diet. In fact, during the 1970s and 80s the dosage range of 200-400 mg per week was considered “standard” for the bodybuilding use of testosterone, nandrolone, boldenone, or methenolone. There is actually little real need for extreme doses of 750-1,000 mg or more of steroid per week, or to supplement an injectable base with additional orals. High doses may produce a faster rate of gain, but are generally not cost effective for the extra muscle they provide. Additionally, high doses of steroids greatly increase cardiovascular strain and the incidence of other side effects.
  • Get Regular Blood Tests. Comprehensive blood testing including an examination of hormones, cholesterol, blood cell concentrations, and enzymes is the most useful tool for assessing the negative health impact of steroid use. Changes in cholesterol, for example, can help quantify for the user what effect a particular drug regimen is having on their cardiovascular health. The individual then has the opportunity to better assess long-term risk if this cycle is to be repeated. At a minimum, blood testing should be conducted before a cycle is initiated, 3 to 4 weeks into a cycle, and a couple of months after a cycle. This allows for 1) a baseline for later comparison; 2) a snapshot of the on-cycle health impact; and 3) an opportunity to assess if natural homeostasis has been restored post-cycle.
  • Use Proper Injection Procedures. Careful attention to correct injection procedures can help eliminate some of the complications associated with nonmedical steroid use. Steroids are given via deep intramuscular injections. The most common site of application is the upper outer quadrant of the gluteus muscle, although the drugs are also commonly injected to the upper outer thigh and shoulder. Site injections (in smaller muscle groups like the biceps, triceps, or calf muscles) for cosmetic purposes are discouraged, as they are technically more difficult to navigate and more prone to complications. Comfortable injection volumes should also be used, generally no more than 3 mL per application. Each injection site should be rotated so that the same muscle is not injected more than once every two weeks. A general focus should be made on cleanliness, including the use of alcohol pads on the vials and skin before injection, and the proper disposal of all needles and empty vials/ampules after use.
  • Watch Your Diet. Anabolic/androgenic steroids can allow an individual significantly more latitude with their diet than normal. The caloric demand typically increases due to the effects of these drugs on muscle mass and metabolism, allowing more calories to be consumed each day without adding fat mass. It is important not to let this latitude affect your health in a negative way. Remember, the use of steroids at physique- and performance-enhancing doses is expected to cause an unfavorable shift in cholesterol levels and other cardiovascular health markers, favoring a higher risk of cardiovascular disease. Simultaneously feeding your body greater amounts of saturated fats, cholesterol, and simple carbohydrates can make the impact of these drugs even worse. Diets low in saturated fats, cholesterol, and simple sugars are recommended, and are known to reduce cardiovascular disease risk. Note, however, that diet alone is not effective at countering the negative cardiovascular effects of steroid use, but dietary restrictions can reduce these risks.
W.Llewellyn, Anabolics